Merck KGaA’s South Korean partnership; Sanofi’s supply chain alliance with DHL
Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. South Korean CDMO Lotte Biologics and Merck KGaA’s life science arm...
View ArticleJ&J’s dealmaker: Plenty of ‘firepower,’ but mostly focused on tuck-in M&A
SAN DIEGO — The head of dealmaking at Johnson & Johnson said that biotech valuations have come back down to more reasonable levels that make it easier to get transactions done, although the company...
View ArticleAbbVie's newly-acquired ADC hits Phase 2 goal in ovarian cancer
AbbVie’s $10.1 billion purchase of ImmunoGen and accompanying antibody-drug conjugate Elahere is already paying off, with the drug scoring a new mid-stage victory. The Chicago-area pharma said...
View ArticleNine years and four generics later, the HIV drug at the center of the Shkreli...
Years after Martin Shkreli kicked off a drug pricing controversy around the HIV drug Daraprim, the price of the drug has not fallen to pre-Shkreli figures despite several generic competitors. There are...
View ArticleSafety, efficacy and dosing questions linger for Lilly's Alzheimer's drug...
The FDA detailed its biggest concerns about Eli Lilly’s experimental Alzheimer’s therapy donanemab ahead of a last-minute advisory committee meeting to convene Monday about the drug. In documents...
View ArticleFDA explains why it rejected Vanda's insomnia application as company faces...
In a rare move, the FDA’s Center for Drug Evaluation and Research publicly disclosed more information about why it rejected a new indication for Vanda Pharmaceuticals’ sleep disorder drug. The company...
View ArticleSenate fails to pass bill codifying access to contraception
The Senate on Wednesday rejected a bill that would codify the right to contraception, with all but two Republicans voting against it. The vote comes at nearly the two-year mark since the Supreme Court...
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Google's parent company Alphabet poaches Eli Lilly CFO; More changes at...
Anat Ashkenazi → It’s been nearly a year since Google’s parent company Alphabet announced that its CFO Ruth Porat would move into the newly created role of president and chief investment officer,...
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Biomea’s early-stage diabetes drug put on full clinical hold, stock crashes
Biomea Fusion’s Phase 1/2 covalent menin inhibitor program in diabetes has been placed on full clinical hold due to “possible” drug-related hepatotoxicity. Liver enzyme elevations were flagged in the...
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#EASL24: Boehringer Ingelheim, Zealand tout key fibrosis data from mid-stage...
Boehringer Ingelheim officially unveiled fibrosis data from a mid-stage trial of its Zealand Pharma-partnered drug in MASH on Friday, after its liver congress abstract was “unintentionally and...
View ArticleIpsen returns to Marengo Therapeutics for new trispecific deal
Ipsen and Marengo Therapeutics are expanding a deal to include two trispecific antibody assets that tackle so-called cold tumors, which do not typically respond well to immunotherapies. The companies...
View Article#EASL24: Aligos, Arbutus, Atea, Barinthus and Bluejay unveil hepatitis results
At this year’s EASL International Liver Congress, Vir took center stage Wednesday to report early Phase 2 data for its hepatitis D approach, and then saw its stock $VIR jump as much as 15% upon data...
View ArticleNeuroscience company Rapport Therapeutics lists on Nasdaq
Rapport Therapeutics expects to raise $154 million from its initial public offering and a concurrent stock sale to private investors, the company announced Thursday evening. Rapport, a neuroscience...
View ArticleAbbVie and Alphabet's Calico added to Operation Warp Speed for rare diseases
AbbVie and Alphabet’s Calico announced Friday that their potential treatment for the rare neurological disease known as vanishing white matter disease will be part of the FDA’s new Operation Warp Speed...
View ArticleItalian antitrust agency investigates Novartis, Biogen and others over...
Italian antitrust authorities are investigating four companies over alleged collusion to delay the introduction of a new biosimilar to Roche’s blockbuster eye drug Lucentis. The Italian Competition...
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FDA greenlights Geron’s imetelstat to treat anemia in certain cancer patients
The FDA approved Geron’s imetelstat to treat certain anemic myelodysplastic syndrome (MDS) patients who are dependent on blood transfusions. The approval comes after the FDA’s Oncologic Drugs Advisory...
View ArticleFederal judge dismisses antitrust claims brought against Bristol Myers by...
A federal judge in New Jersey district court on Thursday dismissed anticompetitive claims brought against Bristol Myers Squibb by a number of insurers over an alleged scheme to delay generic entry for...
View ArticleFDA raises questions about Lilly's Alzheimer's drug; Adcomm votes against...
Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...
View ArticleAmber raises $100M Series A for two-in-one urinary incontinence treatment
Amber Therapeutics completed its $100 million Series A raise to support its implantable therapy for mixed urinary incontinence through a registrational trial in 2026. The proceeds should give Amber a...
View ArticleGSK wins expanded FDA approval for RSV shot in at-risk adults ages 50 to 59
The FDA on Friday expanded GSK’s RSV vaccine to people ages 50 to 59 who are at an increased risk of the virus, marking another win for the blockbuster shot. GSK’s Arexvy, which was first approved in...
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